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McKaizer Institute — Longevity & Wellness Science
Senolytic therapy — clearing senescent zombie cells — is the most directly actionable anti-aging intervention available today. This guide covers every validated protocol: D+Q, fisetin, navitoclax, and how to optimize your senolytic regimen.
2-day
pulsed dosing every 3 months is the proven senolytic protocol — continuous dosing is both ineffective and harmful, making timing everything
Table of Contents
- The Zombie Cell Problem — Why Senescence Accelerates Every Disease of Aging
- The SASP — How Senescent Cells Poison Their Neighbors
- Dasatinib + Quercetin — The Gold Standard Senolytic Protocol
- Fisetin — The Natural Senolytic With Emerging Clinical Evidence
- Navitoclax and Next-Generation Senolytics
- Building Your Senolytic Protocol — Timing, Cycling, Monitoring
- Measuring Senescent Cell Burden — Biomarkers and Testing
- The Future of Senolytic Medicine
- Frequently Asked Questions (20)
The Zombie Cell Problem — Why Senescence Accelerates Every Disease of Aging

The SASP — How Senescent Cells Poison Their Neighbors

“Senolytics are the first drugs that directly remove a fundamental driver of aging rather than treating its symptoms. The clinical translation is moving faster than anyone predicted 5 years ago.”
Dasatinib + Quercetin — The Gold Standard Senolytic Protocol

Fisetin — The Natural Senolytic With Emerging Clinical Evidence

Navitoclax and Next-Generation Senolytics

Building Your Senolytic Protocol — Timing, Cycling, Monitoring

Measuring Senescent Cell Burden — Biomarkers and Testing

The Future of Senolytic Medicine

✦ McKaizer Institute Protocol
Evidence-ranked, actionable steps distilled from the research above.
- Step 1: See the detailed protocol section above.
- Step 2: See the detailed protocol section above.
- Step 3: See the detailed protocol section above.
- Step 4: See the detailed protocol section above.
- Step 5: See the detailed protocol section above.









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