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📅 2026-08-14⏱ 12 min read🔬 Peer-reviewed sources🌐 EN | VI
McKaizer Institute — Longevity & Wellness Science
The longevity supplement market is full of noise. This evidence-ranked guide cuts through the hype — covering NMN, NR, rapamycin, metformin, quercetin, fisetin, and every major compound with honest clinical trial data.
40%
lifespan extension in animal models from rapamycin — the most replicated longevity compound in laboratory aging research
Table of Contents
- How to Think About Longevity Supplements — The Evidence Framework
- Tier 1 Supplements — The Strongest Human Evidence
- NAD+ Precursors — NMN vs. NR vs. IV — The Honest Comparison
- Rapamycin and Metformin — The Prescription Longevity Drugs
- Senolytics — Quercetin, Fisetin and Dasatinib Protocols
- The McKaizer Evidence-Ranked Supplement Stack
- How to Monitor Supplement Efficacy — Biomarkers to Track
- The Future of Longevity Pharmacology
- Frequently Asked Questions (20)
How to Think About Longevity Supplements — The Evidence Framework

Tier 1 Supplements — The Strongest Human Evidence

“The goal is not to sell you supplements. The goal is to give you the truth about what the evidence actually shows — and where the gaps remain.”
NAD+ Precursors — NMN vs. NR vs. IV — The Honest Comparison

Rapamycin and Metformin — The Prescription Longevity Drugs

Senolytics — Quercetin, Fisetin and Dasatinib Protocols

The McKaizer Evidence-Ranked Supplement Stack

How to Monitor Supplement Efficacy — Biomarkers to Track

The Future of Longevity Pharmacology

✦ McKaizer Institute Protocol
Evidence-ranked, actionable steps distilled from the research above.
- Step 1: See the detailed protocol section above.
- Step 2: See the detailed protocol section above.
- Step 3: See the detailed protocol section above.
- Step 4: See the detailed protocol section above.
- Step 5: See the detailed protocol section above.









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